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Combination of vitamin D and estradiol can prevent metabolic syndrome in postmenopausal women

A new study by Chinese researchers shows that the combination of vitamin D and an estrogen such as estradiol can be particularly useful for improving women’s health after menopause, so much that it could also prevent the metabolic syndrome, a set of diseases which in turn increase the risk of stroke, heart disease and diabetes in post-menopausal women.

In the study, published in Menopause, the metabolic syndrome is taken into consideration, which in recent years has become increasingly a concern of doctors and researchers regarding public health. This disease, which affects a percentage of post-menopausal women ranging from 30 to 60%, is, according to previous studies, linked to reduced levels of particular estrogens. These same studies have also led to estradiol-based treatments in particular to prevent problems with certain diseases that can aggravate a person’s health in the long term.

In parallel, the same lack of vitamin D is in turn linked to problems related to the metabolic syndrome, such as obesity, type 2 diabetes and hyperglycemia. The same doctors recommend vitamin D supplements to reduce the risk of metabolic syndrome in the long term. Taking into consideration these previous studies that concerned both estradiol and vitamin D, Chinese researchers have tried to understand if these positive effects could exist if the two elements were taken together.

By performing a cross-sectional study of 616 post-menopausal women between the ages of 49 and 86, the researchers obtained a positive result: vitamin D and estradiol together can prevent diabetes, stroke and heart disease. In particular, vitamin D, according to the researchers, favors the stability of blood pressure and glucose level while low levels of estradiol were associated with cholesterol, triglycerides, bad blood pressure. Low levels of both elements were then linked to a higher risk of metabolic syndrome.